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Aminopurvalanol A

CAS No. 220792-57-4

Aminopurvalanol A ( —— )

Catalog No. M27529 CAS No. 220792-57-4

Aminopurvalanol A is a competitive, selective and cell-permeable inhibitor of cyclin-dependent kinase (CDK) that potently inhibits Cyclin A/cdk2, Cyclin B/cdk1, Cyclin E/cdk2, and P35/cdk5 with IC50 of 33 nM, 33 nM, 28 nM and 20 nM, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 87 Get Quote
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25MG 290 Get Quote
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Biological Information

  • Product Name
    Aminopurvalanol A
  • Note
    Research use only, not for human use.
  • Brief Description
    Aminopurvalanol A is a competitive, selective and cell-permeable inhibitor of cyclin-dependent kinase (CDK) that potently inhibits Cyclin A/cdk2, Cyclin B/cdk1, Cyclin E/cdk2, and P35/cdk5 with IC50 of 33 nM, 33 nM, 28 nM and 20 nM, respectively.
  • Description
    Aminopurvalanol A is a competitive, selective and cell-permeable inhibitor of cyclin-dependent kinase (CDK) that potently inhibits Cyclin A/cdk2, Cyclin B/cdk1, Cyclin E/cdk2, and P35/cdk5 with IC50 of 33 nM, 33 nM, 28 nM and 20 nM, respectively.
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    CDK
  • Recptor
    Gap Junction Protein;FTO
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    220792-57-4
  • Formula Weight
    403.9
  • Molecular Formula
    C19H26ClN7O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC(C)[C@H](CO)Nc(nc1Nc2cc(N)cc(Cl)c2)nc2c1ncn2C(C)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Eleftheriou CG, et al. Meclofenamic acid improves the signal to noise ratio for visual responses produced by ectopicexpression of human rod opsin. Mol Vis. 2017 Jun 16;23:334-345. eCollection 2017.
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